Intranasal drugs possibilities in the treatment of patients with rhinitis medicamentosa

Introduction. The article presents the physiology of nasal breathing, as well problem obstruction and mechanisms its development. Topical issues rhinitis medicamentosa are discussed, based on pathogenic links this condition. It has been established that there is no single treatment regimen for at moment. Objectives . To evaluate effectiveness safety use intranasal drugs in patients with medical rhinitis. Materials methods A comparative study clinical complex preparation Frinozol®, active substances which decongestant phenylephrine antihistamine drug cetirizine, glucocorticosteroid Nosefrin®, their combinations, was carried out medicamentosa. Results results showed Nozefrin®, a combination these leads to decrease frequency decongestants, larger percentage cases or complete cessation by drug-induced Frinozol – Nozefrin somewhat more effective. However, number resume decongestants after some time, need additional courses conservative therapy. In course observational study, we noted excellent good tolerability drugs, patient satisfaction all groups. Conclusions remains unresolved, why search optimal effective schemes disease continues. glucocorticosteroids topical antihistamines can significantly reduce completely abandon use.